Resources for NCI-Sponsored Imaging Trials

Protocol component templates for NCI-held Imaging agents:

• [18F] FMISO
• [18F] FLT
• [18F] FES
• [18F] DCFBC
• [89Zr]-panitumumab

CAEPRs for NCI-held imaging agents:

• [18F] FMISO
• [18F] FLT
• [18F] FES
• Ferumoxytol

IND Resources for Imaging IND agents:

• https://imaging.cancer.gov/programs_resources/IND_regulatory_manufacturing.htm

Other useful protocol templates

• CTEP protocol templates (for phase 1 and 2 and 3 studies, including LOIs and Concept template forms)
• Templates for the Biomarker, Imaging, and Quality of Life Studies Funding Program (BIQSFP)

Additional Resources:

• NCI’s National Clinical Trials Network (NCTN)
• ECOG-ACRIN: one of the funded groups in NCTN charged with the development of advanced imaging in NCTN trials
• Imaging and Radiation Oncology Core (IROC): service-oriented component of the NCTN which provides imaging-related assistance such as Quality Assurance (QA) and Quality Control (QC) to other NCTN members
• ClinicalTrials.gov: registry and results database of publicly and private supported clinical trials conducted around the world
• CCR Molecular Imaging Program
• NIH Clinical Center: Imaging Sciences Program