The intent of this proposed RFP is to develop powerful ultrasound research interfaces that allow extensive control over a wide range of system parameters. These interfaces will be software add-ons to continuously evolving scanner control software. The interface software could run either on the current ultrasound computer systems, or on stand-alone computer systems (PC's) interfaced to the ultrasound scanner control. Although the creation of these interfaces necessarily relies on access to proprietary information, such access can be partly restricted by protective software shells, while still accessing the control parameters. The intent of this concept is to allow research interfaces to be developed by several leading ultrasound manufacturers to maximize the research impact for the ultrasound imaging community.