This page lists past opportunities from CIP.
Requests for Application (RFA) are usually announced with special application dates; there is no possibility for applying after that date. Program Announcements (PA, PAR) may be open for a set period of time, such as 3 years or less; applications submitted in response to Program Announcements may be due on the standard dates (February 1, June1, and October 1) or may have special dates for receipt of applications. Please pay attention to these dates. Contact a CIP staff member if you have questions.
Barbara Y. Croft, Ph.D. (bc129b@nih.gov) at 301-496-9531
The National Cancer Institute (NCI) invites applications from extramural investigators for Small Animal Imaging Resource Programs (SAIRPs). These grants will support (a) shared imaging research resources to be used by cancer investigators, (b) research related to small animal imaging technology, and (c) training of both professional and technical support personnel interested in the science and techniques of small animal imaging.
See full description in NIH Guide:NCI/NIH RFA: CA-04-011
Guoying Liu, Ph.D. (liug@mail.nih.gov) at 301-594-5220
The National Cancer Institute (NCI) invites applications for the pursuit of industry-academic partnerships for development of biomedical imaging systems and methods that are cancer specific. Support for the exchange of scientists between industry and academia can be requested under this initiative.
The goals of this initiative are to
1) Provide grants to help establish and/or expand industry-academic partnerships for development of biomedical imaging systems and methods that are cancer specific whether or not preliminary data or a history of prior collaborations have been established;
2) Support partnerships and pilot projects that may result in commercialization of imaging technologies;
3) Target partnerships that address high-risk/high-gain research and development of new approaches for early cancer detection, diagnosis, image-guided interventions, and assessment of drug therapy.
See full description in NIH Guide: PAR-03-157
Houston Baker, Ph.D. (bakerhou@mail.nih.gov)
PAR-03-124 has been replaced by PA-04-095, which uses Regular Receipt Dates: June 1, October 1, and February 1.
The National Cancer Institute (NCI) and the National Institute for Biomedical Imaging and Bioengineering (NIBIB) invite applications for the development and delivery of novel image acquisition or enhancement technology and methods for biomedical imaging and image-guided interventions and therapy, and which may incorporate limited pilot or clinical feasibility evaluations using either pre-clinical models or clinical studies. This initiative is intended to facilitate the proof of feasibility, development and delivery of novel imaging technologies for early detection, screening, diagnosis, image-guided interventions, and treatment of various diseases, and secondarily to facilitate limited evaluation studies to show proof of concept and functionality.
See full description in NIH Guide:PAR-03-124
See full description in NIH Guide:PA-04-095
Houston Baker, Ph.D. (bakerhou@mail.nih.gov)
PAR-03-125 has been replaced by PA-04-094, which uses Regular Receipt Dates: August 1, December 1, and April 1.
The National Cancer Institute (NCI), the National Institute of Environmental Health Sciences (NIEHS), the National Institute for Biomedical Imaging and Bioengineering (NIBIB) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) invite applications for the development and delivery of novel image acquisition or enhancement technology and methods for biomedical imaging and image-guided interventions and therapy, and which may incorporate limited pilot or clinical feasibility evaluations using either pre-clinical models or clinical studies. This initiative is intended to facilitate the proof of feasibility, development and delivery of novel imaging technologies for early detection, screening, diagnosis, image-guided interventions and treatment of various diseases, and secondarily to facilitate limited evaluation studies to show proof of concept and functionality.
See full description in NIH Guide:PAR-03-125
See full description in NIH Guide:PA-04-094
Guoying Liu, Ph.D. (liug@mail.nih.gov)
The National Cancer Institute (NCI) is announcing the availability of administrative supplemental funds for NCI-funded cancer center grantees (P30s) (domestic only). The primary purpose of this initiative is to provide matching funds to assist in the acquisition of dedicated clinical research imaging equipment, or significant upgrades to existing clinical research imaging equipment (software and/or hardware), in order to optimize the use of imaging as a biomarker in Phase 1 and 2 oncologic trials. The initiative is part of a continuing effort to stimulate and strengthen the use of imaging techniques in cancer research. NCI-funded cancer centers possess the infrastructure, organization, leadership, and integrated multidisciplinary research objectives that enable them to build and incorporate new image technologies into cancer clinical trials.
See full description in NIH Guide:NOT-CA 03-026
Barbara Y. Croft, Ph.D. (bc129b@nih.gov) at 301-496-9531
The National Cancer Institute (NCI) is announcing the availability of administrative supplemental funds for NCI-funded R24, P30, P50, U01, and U54 grantees (domestic only). This administrative supplemental initiative is intended to assist the grantees in creating or extending capabilities in small animal imaging. The initiative is part of a continuing effort to stimulate and strengthen research in small animal imaging techniques and to increase the use of small animal imaging techniques in cancer research. The Instrumentation Grants For Small Animal Imaging Equipment (Administrative Supplements) will provide dedicated funds to buy or upgrade imaging equipment for small animals, emphasizing those modalities that can provide biochemical, molecular, genetic or pharmacological information in vivo.
See full description in NIH Guide:NOT-CA 03-016
Barbara A. Galen, M.S.N., C.R.N.P. (bgalen@mail.nih.gov)
The NCI is requesting competing renewal applications from the American College of Radiology Imaging Network (ACRIN), funded originally through RFA CA-97-020. This will continue a unique ongoing project at its current level and scope to best serve the oncology and imaging science communities. This is particularly important now because ACRIN is currently conducting several ongoing imaging clinical trials critical to the goals of the NCI. The combination of imaging with minimally invasive diagnosis and treatment will enhance clinical practice by limiting disfigurement, trauma and expense.
See full description in NIH Guide:NCI NOT-CA-03-001
Kathy Giuliano, Contract Specialist,
Phone (301) 435-3821,
Fax (301) 402-6699,
Email: kg109o@nih.gov
MaryAnne Golling, Contracting Officer,
Phone (301) 435-3819,
Fax (301) 402-6699,
Email: mg345x@nih.gov
The Cancer Imaging Program (CIP), Division of Cancer Diagnosis and Treatment (DCTD), National Cancer Institute (NCI) plans to develop contracts to support Phase 1 (Safety) and Phase 2 (Preliminary Clinical Efficacy) clinical trials of promising imaging agents. These clinical trials will be used to rapidly evaluate the safety and diagnostic imaging capabilities of promising imaging probes, ligands, radiopharmaceuticals, and contrast agents that are of interest to NCI. The Safety and Preliminary Clinical Efficacy Imaging Clinical Trials contracts will create an infrastructure poised to rapidly evaluate molecularly-targeted imaging agents used to assess therapeutic anticancer agents on their molecular targets and determine clinically relevant correlates. The objectives of this program are: to rapidly conduct clinical trials necessary to assess the safety of promising imaging agents; to rapidly conduct clinical trials necessary to assess the diagnostic imaging capabilities and preliminary efficacy of promising imaging agent to characterize the molecular interactions of new molecular imaging agents with their targets through biopsies, assays, and other appropriate technologies and correlate those effects with clinically-relevant endpoints; to develop new scientific insights into molecular pathways and determinants of the relationship of the targeted imaging agents to therapeutic drug response. Major emphasis shall be on imaging agents which are found to be safe and provide important structural, metabolic, or molecular imaging data which will be important and useful in the management of patients with cancer. These Phase 1 and Phase 2 clinical trials will obtain the necessary data to fulfill the Food and Drug Administration (FDA) criteria to eventually become an approved and potentially marketable imaging agent for specific imaging indications. The studies will explore promising imaging agents, and require rapid initiation, completion, and data reporting. These contracts will also require the ability to implement correlative studies validating the localization of the investigational imaging agents on their molecular target in tumors. Imaging agents may originate from investigators not affiliated with clinical sites. The Government anticipates that five (5) contracts will be awarded on an incrementally funded basis for five years. The size of each trial might vary depending on consultation with the FDA for each specific agent. The typical size for each Safety trail will be approximately 10 patients. The typical size for each Preliminary Clinical Efficacy trail is estimated to be 25 patients. NAICS Code No. 621512 with a size standard of $5.Million.
See full description:RFP: N01-CM-37008
The Cancer Imaging Program (CIP), of the Division of Cancer Treatment and Diagnosis (DCTD) solicits applications for cooperative agreement (U54) awards to establish a Specialized Research Resource Center that will participate as a member of a network of inter-disciplinary, inter- institutional research teams for the purpose of supporting translational research in optical imaging and/or spectroscopy in vivo. The network will operate under the guidance of a Steering Committee (SC). The goal is to organize a consortium with flexibility in scope, funding, and incentives to encourage inter- and intra-team collaborations on translational cancer research. The objective is to accelerate the pace of translational research by developing a consensus process to improve methods for system integration, optimization and validation of next-generation in vivo optical imaging and/or spectroscopy methods and technologies, including contrast agents. The research scope includes feasibility studies for the detection of pre-cancerous lesions, cancer detection and diagnosis, and measurement or prediction of response to therapy.
See full description in NIH Guide:RFA: CA-03-002
Houston Baker, Ph.D. at (hb4s@nih.gov) or Laurence Clarke, Ph.D. at (lclarke@mail.nih.gov).
PAR-01-101/102: Other options for submission
The National Cancer Institute (NCI) and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) invite applications to develop novel in vivo image acquisition or enhancement methods, and incorporate limited pilot or feasibility evaluations using either pre-clinical models or clinical studies. This initiative is intended to facilitate the development of novel imaging technologies for early detection, screening, diagnosis, and image guided treatment of cancer and other diseases. The intent is to stimulate (a) the development of innovative image acquisition and enhancement methods, including high risk/high gain research on technologies that exploit our knowledge of the molecular basis of cancer or other disease, and (b) the integration of these emerging technologies with traditional imaging methods for more effective solutions for health care delivery. A phased innovation award mechanism (R21/R33) is proposed that is suitable for supporting imaging technology development. Applications from academia, industry, and independent research organizations are encouraged. Modifications to this reissued Program Announcement include support for a limited number of system prototypes for pilot or feasibility evaluations using either pre-clinical models or clinical studies. Applicants considering developments for ex vivo or in vitro molecular imaging are encouraged to read announcements PAR-01-105 and PAR-01-107 for Innovative Technologies for the Molecular Analysis of Cancer, listed under NCI Initiatives. Small business applicants with in vivo imaging interests are encouraged to apply under announcement, PAR-01-102.
See full description in NIH Guide:PAR-01-101
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