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Research & Funding

Past CIP InitiativesRSS

This page lists past opportunities from CIP.

Requests for Application (RFA) are usually announced with special application dates; there is no possibility for applying after that date. Program Announcements (PA, PAR) may be open for a set period of time, such as 3 years or less; applications submitted in response to Program Announcements may be due on the standard dates (February 1, June1, and October 1) or may have special dates for receipt of applications. Please pay attention to these dates. Contact a CIP staff member if you have questions.

  • PAR-11-216: Early Phase Clinical Trials in Imaging and Image-Guided Interventions (R21)

    • Release Date: May 24, 2011
    • Application Receipt Date: See below
    • Expiration Date: March 14, 2014
    • Contacts:

      Imaging trials:

      Lalitha K. Shankar, M.D., Ph.D., NCI, Phone: 240-276-6510, (
      Frank I. Lin, M.D., NCI, Phone: 240-276-5932, (

      Image-Guided Intervention trials:

      Keyvan Farahani, Ph.D., NCI, Phone: 240-276-5921, (

      Radiation Therapy trials:

      Bhadrasain Vikram, M.D., NCI, Phone: 240-276-5690, (

    • Application Receipt/Submission Date(s): July 27, 2011; November 10, 2011; March 13, 2012; July 11, 2012; November 13, 2012; March 13, 2013; July 11, 2013; November 13, 2013; March 13, 2014, by 5:00 PM local time of applicant organization.

    This Funding Opportunity Announcement (FOA) is intended to support clinical trials conducting preliminary evaluation of the safety and efficacy of imaging agents, as well as an assessment of imaging systems, image processing, image-guided therapy, contrast kinetic modeling, and 3-D reconstruction and other quantitative tools. As many such preliminary evaluations are early in development, this FOA will provide investigators with support for pilot (Phase I and II) cancer imaging clinical trials, including patient monitoring and laboratory studies. The imaging and Image-guided Intervention (IGI) investigations, if proven successful in these early clinical trials, can then be validated in larger studies through competitive R01 mechanisms, or through clinical trials in the Specialized Programs of Research Excellence (SPOREs), Cancer Center and/or Cooperative Groups.

    See full description in NIH Guide: PAR-11-216;

  • PAR-11-150: Quantitative Imaging for Evaluation of Responses to Cancer Therapies (U01)

    • Release Date: March 14, 2011
    • Application Receipt Date: Standard dates
    • Expiration Date: May 8, 2014
    • Contacts:

      Robert J. Nordstrom, Ph.D. ( at 240-276-5934

    The Cancer Imaging Program, (NCI), solicits applications to promote research on quantitative imaging of tumor response to cancer therapies in clinical trial settings, with the overall goal of facilitating clinical decision making. Proposed projects should include the appropriate development and adaptation/implementation of quantitative imaging methods, protocols and software solutions/tools (using existing commercial imaging platforms and instrumentation), and their application in current and planned Phase 1-2 clinical therapy trials. No support for the clinical trials, as such, will be provided under this initiative. The proposed projects must focus on imaging-derived quantitative measurements of responses to drugs and/or radiation therapy, and/or image-guided interventions. It is anticipated that these research goals will require multidisciplinary efforts. Therefore, this announcement solicits applications from multi-disciplinary teams to include oncologists as well as clinical and basic imaging scientists. The involvement of industrial partners in the development of the quantitative imaging methods is not required, but is strongly encouraged. Awardees form a Quantitative Imaging Network (QIN) to share ideas and approaches to validate and standardize imaging data and related imaging meta-data for quantitative measurements of responses to cancer therapies.

    See the CIP QIN website for a description of the program.

    • No set-aside

    See full description in NIH Guide: PAR-11-150

    Clarification of Scope and Requirements of PAR-11-150: NOT-CA-11-011

  • PA-10-080 and PA-10-079: Image-Guided Interventions (STTR [R41/R42] & SBIR [R43/R44])

    • Release Date: January 08, 2010
    • Application Receipt Date: Multiple dates, see announcements.
    • Expiration Date: January 8, 2013
    • Contacts:

      David Beylin, M.S., NCI, Phone: 301-496-0079, Email:
      Expires January 8, 2013

    These Funding Opportunity Announcements (FOA) support the development and clinical validation of systems for image-guided interventions (IGIs) for cancer. Specifically, the goals of this program are to provide support for: the development and optimization of fully integrated cancer imaging, monitoring, and therapy systems; the validation of integrated IGI systems through clinical evaluations; the development of multiple prototype integrated IGI systems as required for multisite clinical evaluations; and partnerships among small business, large business, and academic clinical centers, as well as small business joint ventures, in order to reach the research goals..

    See full description in NIH Guide: STTR (R41/R42) PA-10-080; SBIR (R43/44) PA-10-079