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Research & Funding

Current Other NCI & NIH InitiativesRSS

This page lists current other NCI and NIH cancer imaging initiatives, including grant mechanisms where industry is encouraged to apply.

For information about the funding process, go to Mechanisms or Guidelines.

The NCI's Division of Extramural Activities provides information about newly approved concepts, which may become RFAs and PAs. Check the Concepts Cleared at the NCI Board of Scientific Advisors Meeting web site for the earliest possible information about future initiatives.

  • PA-14-155: Early Stage Development of Technologies in Biomedical Computing, Informatics, and Big Data Science (R01)

    Source: PA page

    The NIH is interested in promoting a broad base of research and development of technologies in biomedical computing, informatics, and Big Data Science that will support rapid progress in areas of scientific opportunity in biomedical research.  It is expected that this research and development is conducted in the context of important biomedical and behavioral research problems.  As such, applications are intended to develop enabling technologies that could apply to the interests of most NIH Institutes and Centers and range from basic biomedicine and including research to all relevant organ systems and diseases. Major themes of research include collaborative environments; data integration; analysis and modeling methodologies; and novel computer science and statistical approaches.  New opportunities are also emerging as large and complex data sets are becoming increasingly available to the research community.  This initiative aims to address biomedical research areas in biomedical computing, informatics, and Big Data science through the early stage development of new software, tools and related resources, as well as the fundamental research (e.g., methodologies and approaches) leading up to that development.

  • PAR-14-085: Revision applications for research on metabolic reprogramming to improve immunotherapy (R01)

    • Release Date: March 11, 2014
    • Application Receipt Date: Jul 10, 2014; Dec 11, 2014; Jul 10, 2015; Dec 11, 2015; Jul 11, 2016; Dec 14, 2016
    • Expiration Date: Dec 15, 2016
    • Contacts:

      Immune cell metabolism or immunotherapy: T. Kevin Howcroft, Ph.D., 240-276-6200,
      Cancer cell metabolism or metabolomics: Barbara Spalholz, Ph.D., 301-496-7028,
      Metabolic imaging and technology development: Huiming Zhang, Ph.D., 240-276-5979,

    This Funding Opportunity Announcement (FOA) invites research project grant (R01) revision applications from investigators with active NIH R01 research project grant awards to support an expansion of the scope of the funded R01 project grant awards through the addition of one or more new specific aims.  Revision applications are expected to stimulate collaborative research projects to generate a mechanistic understanding of the metabolic processes that support robust anti-tumor immune responses in vivo, determine how the metabolic landscape of the tumor microenvironment affects immune effector functions, and use this information to manipulate (or reprogram) the metabolic pathways used by the tumor, the immune response, or both to improve cancer immunotherapy.

    Companion funding opportunities: PAR-14-087 (P01), PAR-14-086 (U01)