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Research & Funding

Current Other NCI & NIH InitiativesRSS

This page lists current other NCI and NIH cancer imaging initiatives, including grant mechanisms where industry is encouraged to apply.

For information about the funding process, go to Mechanisms or Guidelines.

The NCI's Division of Extramural Activities provides information about newly approved concepts, which may become RFAs and PAs. Check the Concepts Cleared at the NCI Board of Scientific Advisors Meeting web site for the earliest possible information about future initiatives.

  • PAR-16-089: Imaging and Biomarkers for Early Detection of Aggressive Cancer (U01)

    Source: FOA Page

    • Release Date: January 28, 2016
    • Application Receipt Date: Jul 11, 2016; Dec 14, 2016; Jul 10, 2017; Dec 11, 2017; Jul 10, 2018; Dec 11, 2018
    • Expiration Date: Dec 12, 2018
    • Contacts:

      Scientific contacts:
      Richard Mazurchuk, Ph.D. (NCI), Phone: 240-276-7126, Email: Richard.Mazurchuk@nih.gov
      Keyvan Farahani, Ph.D. (NCI), Phone: 240-276-5821, Email: Farahanik@mail.nih.gov

    The purpose of this Funding Opportunity Announcement (FOA) is to: (i) invite researchers to submit collaborative research project (U01) applications to improve cancer screening, early detection of aggressive cancer, assessment of cancer risk and cancer diagnosis aimed at integrating multi-modality imaging strategies and multiplexed biomarker methodologies into a singular complementary approach, and (ii) establish a Consortium for Imaging and Biomarkers (CIB) to perform collaborative studies, exchange information, share knowledge and leverage common resources. The research will be conducted by individual multi-disciplinary research teams, hereafter called Units. All Units are expected to participate in collaborative activities with other Units within the Consortium.

  • PAR-15-334: Development of Innovative Informatics Methods and Algorithms for Cancer Research and Management (R21)

    Source: FOA Page

    • Release Date: January 28, 2016
    • Application Receipt Date: Nov 20, 2015; Jun 14, 2016; Nov 21, 2016; Jun 14, 2017; Nov 20, 2017; Jun 14, 2018
    • Expiration Date: Jun 15, 2018
    • Contacts:

      Juli Klemm, Ph.D., NCI, Phone: 301-480-5778, Email: juli.klemm@nih.gov

    The purpose of this Funding Opportunity Announcement (FOA) is to invite exploratory/developmental research grant (R21) applications for the development of innovative methods and algorithms in biomedical computing, informatics, and data science addressing priority needs across the cancer research continuum, including cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities.  As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative, this FOA encourages applications focused on the development of novel computational, mathematical, and statistical algorithms and methods that can considerably improve acquisition, management, analysis, and dissemination of relevant data and/or knowledge. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, the proposed informatics method or algorithm must have a clear rationale on why it is novel and how it will benefit the cancer research field. Potential applicants who are interested in more downstream tool development, from prototyping to hardening and adaptation, should consult the other companion FOAs listed above.

  • PAR-15-331: Advanced Development of Informatics Technologies for Cancer Research and Management (U24)

    Source: FOA page

    • Release Date: January 28, 2016
    • Application Receipt Date: Nov 20, 2015; Jun 14, 2016; Nov 21, 2016; Jun 14, 2017; Nov 20, 2017; Jun 14, 2018
    • Expiration Date: Jun 15, 2018
    • Contacts:

      Juli Klemm, Ph.D., NCI, Phone: 301-480-5778, Email: juli.klemm@nih.gov

    The purpose of this Funding Opportunity Announcement (FOA) is to invite Cooperative Agreement (U24) applications for advanced development and enhancement of emerging informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum, including cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative, this FOA focuses on emerging informatics technology, defined as one that has passed the initial prototyping and pilot development stage, has demonstrated potential to have a significant and broader impact, has compelling reasons for further improvement and enhancement, and has not been widely adopted in the cancer research field. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, proposed development plans must have a clear rationale on why the proposed technology is needed and how it will benefit the cancer research field. In addition, mechanisms to solicit feedback from users and collaborators throughout the development process should be included. Potential applicants who are interested in early-stage development or informatics resource sustainment should consult companion FOAs listed above.

  • PAR-15-333: Sustained Support for Informatics Resources for Cancer Research and Management (U24)

    • Release Date: January 28, 2016
    • Application Receipt Date: Nov 20, 2015; Jun 14, 2016; Nov 21, 2016; Jun 14, 2017; Nov 20, 2017; Jun 14, 2018
    • Expiration Date: Jun 15, 2018
    • Contacts:

      Juli Klemm, Ph.D., NCI, Phone: 301-480-5778, Email: juli.klemm@nih.gov

    The purpose of this Funding Opportunity Announcement (FOA) is to invite Cooperative Agreement (U24) applications for the continued development and sustainment of high-value informatics research resources to serve current and emerging needs across the cancer research continuum including cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities. As a component of the NCI’s Informatics Technology for Cancer Research (ITCR) Program, this FOA focuses on supporting activities necessary for improved user experience and availability of existing, widely-adopted informatics tools and resources.  This is in contrast to early-stage and advanced development efforts to generate these tools and resources that are supported by companion ITCR FOAs. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, the proposed sustainment plan must provide clear justifications for why the research resource should be maintained and how it has benefited and will continue to benefit the cancer research field.  In addition, mechanisms for assessing and maximizing the value of the resource to researchers and supporting collaboration and/or deep engagement between the resource and the targeted research community should be described.

  • PA-16-040: Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21)s

    Source: FOA page

    • Release Date: January 28, 2016
    • Application Receipt Date: Standard dates apply
    • Expiration Date: Jan 8, 2019
    • Contacts:

      Houston Baker, Ph.D. (NCI), Phone: 240-276-5908, Email: bakerhou@mail.nih.gov

      Please see FOA text for the complete list of scientific/research contacts.

    The purpose of this FOA is to encourage submission of Exploratory/Developmental Bioengineering Research Grants (EBRG) applications which establish the feasibility of technologies, techniques or methods that: 1) explore a new multidisciplinary approach to a biomedical challenge; 2) are high-risk but have high impact; and 3) develop data that may lead to significant future research. An EBRG application may propose hypothesis-driven, discovery-driven, developmental, or design-directed research and is appropriate for evaluating unproven approaches for which there is minimal or no preliminary data. 

  • PAR-15-332: Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01)

    Source: FOA page

    • Release Date: January 28, 2016
    • Application Receipt Date: Nov 20, 2015; Jun 14, 2016; Nov 21, 2016; Jun 14, 2017; Nov 20, 2017; Jun 14, 2018
    • Expiration Date: Jun 15, 2018
    • Contacts:

      Juli Klemm, Ph.D. (NCI), Phone: 301-480-5778, Email: juli.klemm@nih.gov

    The purpose of this Funding Opportunity Announcement (FOA) is to invite Cooperative Agreement (U01) applications for the development of enabling informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this FOA focuses on early-stage development from prototyping to hardening and adaptation. Early-stage development is defined for the purpose of this FOA as the initial development or the significant modification of existing tools for new applications. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, proposed development plans must have a clear rationale on why the proposed technology is needed and how it will benefit the cancer research field. In addition, mechanisms to solicit feedback from users and collaborators throughout the development process should be included.

  • PAR-14-085: Revision applications for research on metabolic reprogramming to improve immunotherapy (R01)

    • Release Date: March 11, 2014
    • Application Receipt Date: Jul 10, 2014; Dec 11, 2014; Jul 10, 2015; Dec 11, 2015; Jul 11, 2016; Dec 14, 2016
    • Expiration Date: Dec 15, 2016
    • Contacts:

      Immune cell metabolism or immunotherapy: T. Kevin Howcroft, Ph.D., 240-276-6200, Howcrofk@mail.nih.gov
      Cancer cell metabolism or metabolomics: Barbara Spalholz, Ph.D., 301-496-7028, spalholb@mail.nih.gov
      Metabolic imaging and technology development: Huiming Zhang, Ph.D., 240-276-5979, zhanghui@mail.nih.gov

    This Funding Opportunity Announcement (FOA) invites research project grant (R01) revision applications from investigators with active NIH R01 research project grant awards to support an expansion of the scope of the funded R01 project grant awards through the addition of one or more new specific aims.  Revision applications are expected to stimulate collaborative research projects to generate a mechanistic understanding of the metabolic processes that support robust anti-tumor immune responses in vivo, determine how the metabolic landscape of the tumor microenvironment affects immune effector functions, and use this information to manipulate (or reprogram) the metabolic pathways used by the tumor, the immune response, or both to improve cancer immunotherapy.

    Companion funding opportunities: PAR-14-087 (P01), PAR-14-086 (U01)

  • PAR-13-137: Bioengineering Research Grants (R01)

    • Release Date: June 20, 2013
    • Application Receipt Date: Standard dates apply: see http://grants.nih.gov/grants/funding/submissionschedule.htm
    • Expiration Date: Standard dates apply: see http://grants.nih.gov/grants/funding/submissionschedule.htm
  • Revisions for Early-Stage Development of Informatics Technology (P01)

    • Release Date: September 20, 2012
    • Application Receipt Date: January 22, 2013, June 18, 2013, November 18, 2013, June 18, 2014, November 18, 2014, June 18, 2015.
    • Expiration Date: June 19, 2015
    • Contacts:

      Jiayin (Jerry) Li, M.D., Ph.D.; Phone: 240-276-6210; Email: jerry.li@nih.gov

      For contact information for specific areas, please consult the FOA for the complete list.

    The purpose of this Funding Opportunity Announcement (FOA) is to invite revisions (formerly called "competing revisions") from currently funded NCI P01 program projects for early-stage development of enabling informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative, this FOA aims to promote interdisciplinary collaboration in the development of innovative computational methods and informatics approaches that are essential for cancer research on all fronts to accelerate scientific discovery and ultimately translate data into knowledge and clinical practice. Applications that focus on data processing and analysis or mathematical/statistical modeling alone without new technology development are not appropriate for this FOA. 

  • Advanced Development of Informatics Technology (U24)

    • Release Date: September 20, 2012
    • Application Receipt Date: January 22, 2013, June 18, 2013, November 18, 2013, June 18, 2014, November 18, 2014, June 18, 2015
    • Expiration Date: June 19, 2015
    • Contacts:

      Jiayin (Jerry) Li, M.D., Ph.D.; Phone: 240-276-6210; Email: jerry.li@nih.gov

      For contact information for specific areas, please consult the FOA for the complete list.

    The purpose of this Funding Opportunity Announcement (FOA) is to invite Cooperative Agreement (U24) applications for advanced development and enhancement of emerging informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge in cancer research. An emerging informatics technology is defined as one that has passed the initial prototyping and pilot development stage, has demonstrated potential to have a significant and broader impact, has compelling reasons for further improvement and enhancement, and has not been widely adopted in the cancer research field. If successful, these technologies would accelerate research in cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities. This FOA is one component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative whose central mission is to promote research-driven informatics technology development.  Potential applicants who are interested in early-stage development should consult companion FOAs listed on the previous page.  Applications that focus on informatics data processing and analysis or mathematical/statistical modeling alone without informatics technology development are not appropriate for this FOA.