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THE LIDC AND ITS MISSION
The LIDC is a Consortium of 5 Institutions funded by the National Cancer Institute under the Cancer Imaging Program (CIP). These institutions are:
- The University of Chicago
- University of Iowa Roy J. and Lucille A. Carver School of Medicine
- The David Geffen School of Medicine at UCLA
- Weill Medical College of Cornell University
- The University of Michigan Medical School
Members of other institutions also participate in key roles such as statistical design.
MISSION
The mission of the LIDC is the sharing of lung images, especially low-dose helical CT scans of adults screened for lung cancer, and related technical and clinical data for the development and testing of computer-aided diagnosis (CAD) technologies.
PRINCIPAL GOALS
To establish standard formats and processes for managing thoracic CT scans and related technical and clinical data for use in the development and testing
of CAD algorithms.
To develop an image database as a web-accessible international research resource for the development, training, and evaluation of CAD methods for lung cancer detection and diagnosis using helical CT.
CHALLENGES IN CONSTRUCTING THE DATABASE
- Defining a Nodule- The Nodule Visual Library
Written definitions are problematic. We are developing a Nodule Visual Library. This will attempt to describe the full spectrum of "Focal Abnormalities," of which Nodules are a subset.
There are 3 images portraying a lung scar, a speculated nodule and a calcified nodule.
- Establishing Spatial "Truth" for Nodule Boundary
Consensus on boundary is also difficult to arrive at (see below).
We will assess reader variability of contours and construct a probabilistic description of boundaries.
Three images are shown, of a speculated nodule with contours drawn by 2 experts, on showing all the components, and the other including only solid/core part.
VISIT THIS EXHIBIT FOR CME CATEGORY 1 CREDIT
MONDAY THRU THURSDAY
12:15 pm to 1:15 pm
At that time, LIDC members will be here to describe
- The efforts of the consortium,
- This exhibit and any other questions you might have
- Demonstrate some of the boundary drawing/contouring tools
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DATABASE IMPLEMENTATION STEPS
TASKS COMPLETED (see current reports on website):
(1) Specification of Inclusion Criteria:
(a) CT scanning technical parameters
(b) Patient inclusion criteria
(2) Process Model for Data collection
(a) Determination of Spatial "truth" Using Blinded and Unblinded reads
(3) Development of Boundary Drawing/Contouring Tools
TASKS ONGOING (expected completion date):
(1) Definition of Nodule - Nodule Visual Library (Feb 04)
(2) Evaluation of Boundary Variability (Feb 04):
(a) Inter-Reader Variability
(b) Boundary Drawing Tool Variability
IMPLEMENTATION TIMELINE
| Task | Date Expected |
| Specify Complete Data Model | Jan 04 |
Specify LIDC internal workflow
| | Data passing, Performing reviews | Jan 04 |
| Initial implementation, testing of workflow | Jan/Feb 04 |
| Database Implementation- Start | Jan 04 |
| Database Implementation- Completion | Mar/Apr 04 |
| Implementing Public Interface to Database | Apr/May 04 |
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| PUBLIC ACCESS TO CASES - EXPECTED | MAY/JUN 04 |
LIDC WEBSITE
Overview - www3.cancer.gov/bip/steer_lidc.htm
Committee Reports - www3.cancer.gov/bip/lidc_comm.htm
Contains publicly available documents describing inclusion criteria, process model details, etc.
AUTHORS
Samuel G. Armato III, PhD1, Laurence P. Clarke, PhD2, Geoffrey McLennan, MD3, Michael F. McNitt-Gray, PhD4 , Chuck R. Meyer, PhD5, David Yankelevitz, MD6, Denise R. Aberle, MD4, Barbara Y. Croft, PhD2, Claudia I. Henschke, MD, PhD6, Eric A. Hoffman, PhD3, Ella A. Kazerooni, MD5,
Heber MacMahon, MD1, Anthony P. Reeves, PhD6 , Nicholas Petrick, PhD7, Robert Wagner, PhD7, David Gur, PhD8, Lori Dodd, PhD2, Carl Jaffe, MD2, Peyton H. Bland, PhD5, Keith Brautigam, BA3, Matthew S. Brown, PhD4, Barry De Young, MD3, Roger Engelmann, MS1, Andinet Enquobahrie, MS6,
Carey E. Floyd, Jr., PhD9, Junfeng Guo, PhD3, Aliya Husain, MD1, Gary Laderach5, Charles E. Metz, PhD1, Brian Mullan, MD3, Richard Pais, BS4, Christopher Piker, BS3, James Sayre, DrPH4 , Adam Starkey1
1Department of Radiology, University of Chicago, 2Cancer Imaging Program,
National Cancer Institute, 3 University of Iowa Roy J. and Lucille A. Carver School of Medicine, 4 David Geffen School of Medicine, University of California, Los Angeles, 5Department of Radiology, University of Michigan Medical School, 6Weill Medical College of Cornell University, 7U.S. Food and Drug Administration, 8Department of Radiology, University of Pittsburgh, 9Department of Radiology, Duke University
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