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Newsletter No. 34 -- July, 2000

ITEMS OF INTEREST TO THE IMAGING RESEARCH COMMUNITY:

CIP Web Site: http://www.cancer.gov/bip

NIH

  1. DEVELOPMENT OF CLINICAL IMAGING DRUG ENHANCERS (DCIDE) (NCI) (Notice:CA-00-018)
    The National Cancer Institute (NCI) announces a new program called Development of Clinical Imaging Drug Enhancers (DCIDE). DCIDE will make available to investigators, on a competitive basis, the preclinical development contract resources of NCI. The goal of DCIDE is the development of promising imaging molecular probes or enhancers (contrast agents) that are otherwise unlikely to undergo further development leading to Investigational New Drug (IND) application. DCIDE will assist the selected investigators by providing or facilitating any (or all) of the preclinical development requirements, including, for example, pharmacokinetics, dosimetry, and IND-directed toxicology. Assistance may also take the form of direction regarding regulatory affairs and access to probes for approved preclinical protocols.
    URL: http://www.cancer.gov/bip/dcide.htm
  2. INTEGRATIVE AND COLLABORATIVE APPROACHES TO RESEARCH (PA-00-099) -NIGMS
    This is a re-announcement of PA-99-109, release date June 3, 1999. The purpose of this Program Announcement (PA) is to facilitate collaborative and interdisciplinary approaches to significant biological problems by investigators at different institutions. This initiative will use the R24 grant mechanism, designed for groups of currently funded investigators working on a common problem, to 1) attract and coordinate expertise in different disciplines and approaches and 2) to provide access to specialized resources and equipment. This mechanism must involve investigators at different institutions and must introduce new collaborative and interactive activities that will further the shared research goals and significantly enhance what could be accomplished with the individual investigators' grant support. See the announcement for other NIGMS initiatives.
    URL: http://grants.nih.gov/grants/guide/pa-files/PA-00-099.html
  3. PLANNING GRANTS: NATIONAL PROGRAMS OF EXCELLENCE IN BIOMEDICAL COMPUTING (PRE-NPEBC) (PAR-00-102) - Multiple Institutes and Centers
    Letter of Intent Receipt Date: February 27, June 27, and October 27 annually
    Application Receipt Date: March 27, July 27, and November 27 annually
    Participating Institutes and Centers of the National Institutes of Health (NIH) invite applications for P20 planning grants that lead to the establishment of National Programs of Excellence in Biomedical Computing. A subsequent series of solicitations will be issued to invite applications for National Programs of Excellence in Biomedical Computing (NPEBC).
    URL: http://grants.nih.gov/grants/guide/pa-files/PAR-00-102.html
  4. INNOVATIONS IN BIOMEDICAL INFORMATION SCIENCE AND TECHNOLOGY: PHASED INNOVATION AWARD (R21/R33 - PA-00-117) (SBIR/STTR - PA-00-01) (NIH)
    Letter of Intent Receipt Dates: October 27, February 27, and June 27 annually
    Application Receipt Dates: November 27, March 27, and July 27 annually (This solicitation begins with the November 27, 2000, receipt date and ends with the November 27, 2002, receipt date.)
    Participating Institutes and Centers of the National Institutes of Health invite applications for innovative research in biomedical information science and technology to promote the progress of biomedical research.
    URL: http://grants.nih.gov/grants/guide/pa-files/PA-00-117.html
    SBIR/STTR URL: http://grants.nih.gov/grants/guide/pa-files/PA-00-118.html
  5. FUNCTIONAL MRI AND INTERVENTION FOR COGNITIVE DEFICITS AFTER TRAUMATIC BRAIN INJURY (RFA-NS-01-007)
    Letter of Intent Receipt Date: December 15, 2000; Application Receipt Date: February 15, 2001
    Traumatic brain injury (TBI) is a prevalent and dangerous occurrence in the United States, with approximately 2 million new cases each year. The NINDS, the National Center for Medical Rehabilitation Research in NICHD, and NIMH seek research devoted to functional imaging of brain activity in brain-injured individuals with complex cognitive deficits that constitute altered executive functioning. This RFA will use the National Institutes of Health (NIH) individual research grant (R01) award mechanism. The NINDS, NICHD, and NIMH intend to commit a total of approximately $4.0 million in FY 2001 to fund eight to ten new and/or competitive continuation grants in response to this RFA.
    URL: http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-01-007.html
  6. ANCILLARY STUDIES IN HEART, LUNG, AND BLOOD DISEASE TRIALS (HL-00-012) - NHLBI
    Letter of Intent Receipt Date: One month prior to application receipt dates
    Application Receipt Date: Applications will be accepted every three (3) MONTHS on the following receipt dates: September 11 and December 11 of 2000; March 9, June 11, September 10, and December 10 of 2001; and March 11 and June 10 of 2002.
    The overall goal of this initiative is to solicit research grant applications to conduct mechanistic studies in clinical trials related to heart, lung and blood diseases. Specifically, this initiative focuses on the utilization of patients and patient materials from such trials to study the mechanisms underlying the interventions, the mechanisms of disease pathogenesis, surrogate markers or biomarkers of disease activity and therapeutic effect and the mechanisms of human cardiopulmonary and hematologic function.
    URL: http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-00-012.html
  7. VISIBLE HUMAN PROJECT ANATOMICAL METHODS - NIH
    SOL BAA RFP NLM 00-103/DJH POC Daniel J. Hartinger, Contracting Officer, 301/496-6546.
    The National Library of Medicine, NIDCR, NEI, NIDCD, NCI, and the National Science Foundation seeks to obtain competitive proposals for the award of one or more completion type, cost reimbursement contracts. The goal of the project is to rectify anatomic methodology issues cited as negative outcomes from anatomic observations (lessons-learned) of the Visible Human Project (VHP). Offerors may submit a research & development contract proposal which addresses one or more of six identified project area topics of interest to imagers.
    URL: http://alerts.sciencewise.com/swalert/nih/nlm/opp/06190002.htm
  8. ANCILLARY STUDIES TO NIMH MULTI-SITE CLINICAL TRIALS (PAR-00-095) (NIMH)
    The National Institute of Mental Health (NIMH) recently issued four contracts to support multi-site clinical trials in schizophrenia, Alzheimer's disease, bipolar disorder, treatment resistant depression, and adolescent depression. Information about these trials is available on the NIMH website at http://www.nimh.nih.gov/studies/index.cfm NIMH invites investigator-initiated research project applications for ancillary studies that extend the utility of the national resource created in these trials.
    URL: http://grants.nih.gov/grants/guide/pa-files/PAR-00-095.html

OTHER GOVERNMENT AGENCIES

  1. AHRQ HEALTH SERVICES RESEARCH (PA-00-111)
    The mission of the Agency for Healthcare Research and Quality (AHRQ), formerly known as the Agency for Health Care Policy and Research (AHCPR), is to enhance the quality, appropriateness, and effectiveness of health services, and access to such services, through the establishment of a broad base of scientific research and through the promotion of improvements in clinical and health systems practices, including the prevention of diseases and other health conditions.
    URL: http://grants.nih.gov/grants/guide/pa-files/PA-00-111.html
  2. FISCAL YEAR 2000 DOD DEFENSE HEALTH RESEARCH PROGRAM - DOD COMMERCE BUSINESS DAILY ISSUE OF JUNE 2, 2000 PSA#2613 SOL CBD-DHP-0531 POC
    Craig D. Lebo, Contracting Officer, 301-619-2036. The Defense Appropriations Act of Fiscal Year 2000 (FY 00) provides $25M to support peer-reviewed research on military relevant health-related topics. Proposals are being solicited from agencies of local, state, and federal governments; educational institutions; nonprofit organizations; and private industry on the a number of topics, including Cancer Research and Treatment, Digital Mammography Imaging. FY 00 individual awards will normally be limited to a total of $2M inclusive of direct and indirect costs, with a maximum performance
    URL: http://www-usamraa.army.mil
  3. Initiative on Sensing and Imaging Technologies for Multi-Use Applications
    The Engineering Directorate of the National Science Foundation (NSF) announces an Initiative on Sensing and Imaging Technologies for Multi-use Applications. This focused initiative seeks high risk/high return studies involving the application of sensing/imaging technologies to health monitoring, surface and subsurface monitoring, process control and transport phenomena, and distributed sensing and control. Several other NSF directorates also support research on sensors.
    URL: http://www.nsf.gov/cgi-bin/getpub?nsf00106
  4. DOD SBIR/STTR Web Site
    URL: http://www.acq.osd.mil/sadbu/sbir/

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Cancer Imaging Program
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