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CIP Newsletter No 128 - October 2010

CIP Newsletter No 128

CIP CANCER RESEARCH IMAGING CAMP
Washington University, St. Louis, MO, June 19-24, 2011
Application deadline: February 11, 2011
Postdoctoral fellows and early career-level faculty in fields related to basic cancer biology are invited to apply for a special intensive course on in vivo imaging techniques.
URL: http://imaging.cancer.gov/NewsAndMeetings/workshops/CRIC

EXCEPTIONAL, UNCONVENTIONAL RESEARCH ENABLING KNOWLEDGE ACCELERATION (EUREKA) (8 ICS INCLUDING NCI) (R01) (RFA-GM-11-003)
Application Receipt Date: October 21, 2010
This FOA solicits R01 applications proposing exceptionally innovative research on novel hypotheses or difficult problems, solutions to which would have an extremely high impact on biomedical or biobehavioral research that is germane to the mission of one or more of the participating Institutes. This FOA is for support of new projects, not continuation of projects that have already been initiated.
URL:  http://grants.nih.gov/grants/guide/rfa-files/RFA-GM-11-003.html

TUMOR MICROENVIRONMENT NETWORK (TMEN) (U54) (NCI, NINDS) (RFA-CA-10-021)
Letters of intent receipt date: December 20, 2010
Application Receipt Date: January 20, 2011
This FOA is designed to promote research on tumor microenvironment with the focus on understanding the role of host stroma in tumorigenesis and responses to treatment. Through this FOA, the 2 institutes invite cooperative agreement applications from groups of investigators interested in forming Research Centers serving as components of an interactive NCI Tumor Microenvironment Network (TMEN). The main scientific objectives of TMEN are: 1) to generate a comprehensive understanding of composition of the stroma in normal tissues as well as its roles in tumor initiation, progression, and metastasis; 2) to delineate mechanisms of tumor-stroma interactions in human cancer; and 3) to identify the mechanism(s) by which tumor stroma may affect responses to treatment. In addition to these general NCI priorities, NINDS is particularly interested in research programs relevant to primary brain tumors or peripheral nervous system tumors. TMEN members will be expected to participate in collaborative efforts (to be developed within TMEN) that are directed at: 1) developing resources and reagents; 2) developing novel technologies; and 3) outreach activities.  TMEN infrastructure is expected to establish repositories of critical reagents, resources, and information as well as promote and facilitate interdisciplinary collaborations both within and outside the Network.  Among other general and NCI-specific areas of emphasis is Imaging the tumor microenvironment during tumor initiation, angiogenesis, inflammation, invasion, migration, metastasis, and dormancy, as well as in response to therapies.
URL:  http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-10-021.html

CANCER DIAGNOSTIC AND THERAPEUTIC AGENTS ENABLED BY NANOTECHNOLOGY (SBIR [U43/U44]) (NCI) (PAR-10-286)
Application Receipt Date(s): December 7, 2010; March 10, 2011; July 7, 2011; November 10, 2011; March 8, 2012; July 9, 2012; November 8, 2012; March 8, 2013; July 8, 2013
This Funding Opportunity Announcement (FOA), issued by the National Cancer Institute (NCI), National Institutes of Health (NIH), invites Small Business Innovation Research (SBIR) cooperative agreement applications from small business concerns (SBCs) that propose to develop new, or to improve existing application(s) of nanotechnology-based therapeutics or/and in vivo diagnostics.  This FOA will specifically support pre-clinical optimization and testing of these cancer-relevant nanotechnology applications against the intended cancer type.  Among the examples of possible research areas are in vivo imaging agents and diagnostic tools for cancer detection at the earliest stages.
URL:   http://grants.nih.gov/grants/guide/pa-files/PAR-10-286.html

ROBOTICS TECHNOLOGY DEVELOPMENT AND DEPLOYMENT [RTD2] (R43) (NCI, DOD,DHS, USDA, NSF)(PAR-10-279)
Letter of intent date:  November 20, 2010
Application Receipt Date: December 20, 2010
The sponsoring agencies encourage SBIR Phase I applications for the development of technologies that will advance the field of robotics.  Scientific interests for this joint-agency FOA include, but are not limited to, research directed towards innovations or advancements in robotic technologies and devices for: Robotics for Home Healthcare, Personalized Care for Special-needs Populations, and Robotic Wellness/Health Promotion; Robot-Assisted Recovery, Rehabilitation, and Behavioral Therapy; High-throughput Robotics Technologies; Better Than Biology Actuators; Patient Mobility and Rehabilitation Robotics; Dexterous Manipulators with Tactile Feedback; Multi-Agent Command, Coordination, and Communication; Robotic Co-Worker Assistive Technologies; robotics to render improvised explosive devices safe; and robotics for cross border tunnels.
URL:  http://grants.nih.gov/grants/guide/pa-files/PAR-10-279.html

DEVELOPMENT OF COMPREHENSIVEAND CONCEPTUALLY-BASED MEASURES OF PSYCHOSOCIAL STRESS (R21) (RFA-HL-11-034)
Letters of Intent Receipt Date: September 14, 2010
Application Receipt Date: October 14, 2010
This FOA issued by the NIH Basic Behavioral and Social Sciences Opportunity Network (OppNet) solicits Research Project Grant (R21) applications from institutions and organizations that propose to develop and test conceptually-based and comprehensive measures of psychosocial stress that can be applied across species and across the lifespan.  A number of emerging technologies and methodologies may be useful in the development of conceptually-based measures of stress, among them neuroimaging, that can incorporate a range of constructs at different levels into a single, comprehensive measure of psychosocial stress.
URL:  http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-11-034.html

SCALABLE ASSAYS FOR UNBIASED ANALYSIS OF NEUROBIOLOGICAL FUNCTION (R01) (NIMH, NINDS) (RFA-MH-11-040)
Letters of intent due date: October 17, 2010
Application Receipt Date(s): November 17, 2010
This FOA encourages R01 applications to develop novel, robust analytical platforms using in vitro assays to reveal changes in neuronal and/or glial function.  The goal is to adapt state-of-the-art measures of basic cellular processes or molecular events that are key mediators of brain function with the intent to probe mechanisms and/or perturbations in an unbiased and efficient manner.  Examples of suitable research topics include novel adaptation of assays for imaging and quantifying dynamic changes in the localization of signaling molecules or intracellular compartmentalization.
URL:  http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-11-040.html

NEUROSCIENCE RESEARCH ON DRUG ABUSE [(R01)(PA-10-268)] [(R21)(PA-10-269)] [(R03)(PA-10-270) (NIDA)
Application Receipt Date(s): Multiple receipt dates, see announcements
This NIDA FOA encourages grant applications relevant to the understanding of the process(es) and mechanisms underlying drug abuse and addiction, including use, dependence, addiction. This research may be conducted using model systems, animals, and/or humans.  Circuit-level approaches may delineation of circuits through the use of neuroimaging techniques such as optogenetics, two-photon imaging, or in vivo spectroscopy, PET- or BOLD imaging.  There is a need for new ligands for neuroimaging studies as well as novel, innovative molecular probes/ligands for receptors, transporters, enzymes, and other neurobiological targets that are associated with drug addiction. 
URL (R01):  http://grants.nih.gov/grants/guide/pa-files/PA-10-268.html
URL (R21):  http://grants.nih.gov/grants/guide/pa-files/PA-10-269.html
URL (R03):  http://grants.nih.gov/grants/guide/pa-files/PA-10-270.html

EARLY CAREER AWARD IN CHEMISTRY OF DRUG ABUSE AND ADDICTION (ECHEM) NIDA (R21/R33) (NIDA) (PAS-10-274)
Application Receipt Date(s): Multiple dates, see announcement.
NIDA, through the issuance of this FOA, with set aside funds (PAS), invites Phased Innovation (R21/R33) grant applications from new-to-NIH investigators into basic chemistry research applied to drug abuse and addiction.  NIDA invites newly independent investigators and investigators who have not had previous NIH funding to submit applications for research projects related to NIDA's mission.  Applicants responding under this FOA may propose new probes either based on original concepts/hypotheses or on the existing SAR literature. 
URL:  http://grants.nih.gov/grants/guide/pa-files/PAS-10-274.html

NIDCD OTOPATHOLOGY RESEARCH COLLABORATION NETWORK (U24) (NIDCD) (RFA-DC-11-003)
Letters of intent receipt date: November 1, 2010
Application Receipt Date: December 01, 2010
This Funding Opportunity Announcement (FOA) issued by the National Institute on Deafness and Other Communication Disorders (NIDCD), National Institutes of Health (NIH) will promote timely human otopathology research relevant to new discoveries in genetics, physiology and disease. Emphasis is on collaborative infrastructure for research on human ear disorders.  Explicit collaborations to link modern biology, imaging, and informatics technologies with patient history and pathology will provide a new approach to otopathology.
URL:  http://grants.nih.gov/grants/guide/rfa-files/RFA-DC-11-003.html

KNOCKOUT MOUSE PHENOTYPING (U54) (RFA-RM-10-011) AND PROJECT DATABASE (RFA-RM-10-012) (15 ICS NOT INCLUDING NCI)
Letter of intent due: September 15, 2010 (note that letters are intent are appreciated, but not required)
Application Receipt Date: November 10, 2010
Notice of Pre-application Meeting and Correction for Request for Applications (RFA-RM-10-011, RFA-RM-10-012, and RFA-RM-10-013) for the Knockout Mouse Phenotyping (U54), Project Database (U54), and Production and Cryopreservation (U42).  (NOT-RM-10-015)
Pre-Application Meeting: October 12, 2010
This meeting will take place at the NIH Twinbrook Conference Facility (5635 Fisher's Lane, Terrace Level) in Rockville, MD from 12:00 PM to 2:00 PM on Tuesday, October 12, 2010. This meeting is open to the public and will be available via teleconference. In order to receive the teleconference number, please send the information outlined below in an email to komp2@mail.nih.gov. All prospective applicants are invited to attend this meeting.
This FOA issued by the NIH Office of Strategic Coordination, Office of the Director solicits grant applications to perform broad phenotyping of the International Knockout Mouse Consortium's (IKMC) mutant mice. The overall objective of this FOA is to produce functional information for each protein-coding gene in the mammalian genome.
URL for public meeting announcement:  http://grants.nih.gov/grants/guide/notice-files/NOT-RM-10-015.html
URL:  http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-10-011.html
URL for Project Database: http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-10-012.html

PILOT AND FEASIBILITY CLINICAL RESEARCH GRANTS IN ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES (R21) (NIAMS) (PAR-10-282)
Application Receipt Date(s): Nov 18, 2010, March 1, 2011, July 1, 2011; Nov 1, 2011, March 1, 2012, July 2, 2012; Nov 1, 2012, March 1, 2013, July 1, 2013
This FOA encourages exploratory/developmental clinical research related to the prevention or treatment of arthritis and musculoskeletal and skin diseases, conditions, and/or injuries.  Specific examples of research areas of interest include developing clinical biomarkers and novel imaging modalities that reliably predict disease progression and treatment outcomes and can be used as surrogate endpoints in clinical trials.
URL:  http://grants.nih.gov/grants/guide/pa-files/PAR-10-282.html

SBIR PHASE I CONTRACT SOLICITATION PHS 2011-1 (NIH and CDC)
Receipt date for proposals:   November 8, 2010
These topics might be for interest to the imaging community.  Please check other topics.
298 Low-Field Electron Paramagnetic Resonance Imaging Device to Optimize Development of Anti-Angiogenic Therapeutics in Cancer Animal Models (NIH TT)
(Fast-Track proposals will not be accepted. Phase II information is provided only for informational purposes to assist Phase I offerors with their long-term strategic planning.)
Number of anticipated awards: 1
Budget (total costs): Phase I: $200,000 for 9 months; Phase II: $1,000,000 for 2 years
300 Therapeutics and Theranostics Based on Nanotechnology
(Fast-track proposals will be accepted.)  Number of Anticipated Awards: 3-5
Budget (total costs): Phase I: $200,000 for 9 months; Phase II: $1,000,000 for 2 years
301 Nanotechnology Sensing Platforms for Improved Diagnosis of Cancer
(Fast-Track proposals will be accepted.)  Number of Anticipated Awards: 3-5
Budget (total costs): Phase I: $200,000 for 9 months; Phase II: $1,000,000 for 2 years
305 Novel Digital X-ray Sources for Cancer Imaging Applications
(Fast-Track proposals will not be accepted. Phase II information is provided only for informational purposes to assist Phase I offerors with their long-term strategic planning.)  Number of Anticipated Awards: 2-3
Budget (total costs): Phase I: $250,000 for 9 months; Phase II: $1,500,000 for 2 years
306 Development of Innovative Algorithms/Software for Processing & Analysis of In Vivo Images in Oncology
(Fast-Track proposals will not be accepted. Phase II information is provided only for informational purposes to assist Phase I offerors with their long-term strategic planning.)  Number of Anticipated Awards: 2-4
Budget (total costs): Phase I: $200,000 for 9 months; Phase II: $1,000,000 for 2 years
307 Novel Imaging Agents to Expand the Clinical Toolkit for Cancer Diagnosis, Staging, and Treatment
(Fast-Track proposals will not be accepted. Phase II information is provided only for informational purposes to assist Phase I offerors with their long-term strategic planning.)  Number of Anticipated Awards: 3-5
Budget (total costs): Phase I: $250,000 for 9 months; Phase II: $1,500,000 for 2 years
URL for Announcement Book: http://grants.nih.gov/grants/funding/sbircontract/PHS2011-1.pdf    
URL for SBIR page:  http://grants.nih.gov/grants/funding/sbir.htm  

Other Funding Agencies
UNSOLICITED PROPOSALS TO NSF PROGRAMS THAT ADDRESS THE INTERDISCIPLINARY TOPIC OF PHYSICAL AND ENGINEERING SCIENCES IN ONCOLOGY (NSF 10-065)
Application deadline: October 31, 2010
Historically, the fields of cancer biology and clinical oncology have been dominated by researchers with classical training in the basic and clinical life sciences. More recently, the field has expanded to include physical and engineering scientists, whose background and expertise are complementary to those possessed by life scientists, leading to the recognition that significant advancements in the fundamental understanding of cancer diseases are possible through multidisciplinary research that involves experts in the physical and engineering science disciplines.
To foster fundamental research in this field, NSF, in collaboration with the NCI's Office of Physical Sciences in Oncology (http://cssi.cancer.gov/psoc.asp ), will accept and review investigator-initiated proposals. It is anticipated that programs in the Engineering Directorate, including Divisions of Civil, Mechanical, and Manufacturing Innovation (CMMI), Chemical, Bioengineering, Environmental, and Transport Systems (CBET), and Electrical, Communications, and Cyber Systems (ECCS), and the Mathematical and Physical Sciences Directorate's Division of Materials Research (DMR, Biomaterials Program) will accept proposals on this interdisciplinary topic. Proposals should be submitted to the relevant NSF program; submitted proposals will follow standard NSF policies and procedures for merit review and must comply with all requirements identified in the current NSF Grant Proposal Guide.  PIs are encouraged to contact the appropriate NSF program director via email or telephone before submission to ensure that the identified program is participating in this program and to inform the NSF program director (PD) of the principal investigator's (PI's) plan to submit in response to this dear colleague letter (DCL).
URL:  http://www.nsf.gov/pubs/2010/nsf10065/nsf10065.jsp?WT.mc_id=USNSF_25&WT.mc_ev=click

Notices

My NCBI: Move It or Lose It!
Citation information that has been manually entered into eRA Commons will no longer be available as of eRA's October software release (currently scheduled for October 21-22, 2010). These citations are identified in Commons currently by a "Citation Source" of "PD/PI Entered." If you wish to retain this information for future use (i.e., in a future eSNAP report), these citations will have to be moved to My Bibliography, which is accessed through a My NCBI account. For more information on the eRA Commons and My NCBI integration, see NOT-OD-10-103 and "An Easier Way to Manage Citations."
URL:  http://nexus.od.nih.gov/insider/insider.aspx?ID=504&Month=08&Year=2010

Tailor Your Biosketches Early, Coordinate with Key Personnel
Each biosketch includes a personal statement that describes why each member of the team's experience and qualifications make him/her particularly well-suited for the role in the project. The PI should let the other members of the team know well in advance of the application due date that it is time to update their biosketches.  Remember that the publications in the biosketch that fall under the NIH Public Access Policy need to include the proper identifiers.  All the citation information will be managed with My NCBI's My Bibliography tool, so it can be used as a reference when preparing the biosketch. 
URL:  http://nexus.od.nih.gov/insider/insider.aspx?ID=504&Month=08&Year=2010  

CIP Announcements
CIP DCIDE PROGRAM MORPHS INTO NExT
The Cancer Imaging Program's DCIDE program for providing data to investigators for their IND filings is being absorbed by the NCI Experimental Therapeutics Program (NExT).  Submissions are due quarterly, on the 15th of February, May, August and November. 
URL: http://next.cancer.gov/ 
 
GUEST AUTHOR OPPORTUNITIES IN THE NIH MICAD DATABASE
The Molecular Imaging and Contrast Agent Database (MICAD) program has been developed as a key component of the NIH Molecular Imaging Roadmap to provide freely accessible online scientific information on in vivo molecular imaging and contrast agents. To accelerate expansion of the database to include all published agents, the MICAD program has implemented a procedure for members of the imaging community to write and submit entries (chapters) as guest authors to the database. All members of the imaging community are encouraged to consider this guest author opportunities. For further information, please contact the MICAD staff at micad@ncbi.nlm.nih.gov. Individual guest authors will be provide with detailed instructions, style guidelines, and a chapter template. The name of the contributing author(s) will be acknowledged and included in the MICAD online publication.
URL: http://micad.nih.gov
URL: http://bookshelf.ncbi.nlm.nih.gov/books/bookres.fcgi/micad/infoguest.html)

Meetings
ISMRM Workshop on MR Safety: RF Heating of the Human in MRI
October 15-17, 2010, Stillwater, MN
URL:  http://www.ismrm.org/workshops/Safety_10/

International Conference on the Ultrasonic Measurement and Imaging of Tissue Elasticity
October 16-19, 2010, Cliff Lodge Snowbird Ski and Summer Resort, Snowbird, UT
URL:  http://www.elasticityconference.org/ 

2nd International Symposium on MR-guided Focused Ultrasound
October 17-20, 2010, Westfield Marriott Washington Dulles, Chantilly, VA
URL:  http://www.fusfoundation.org/Symposium-2010/mrgfus-2010

7th Annual Memphis BioImaging Symposium
November 4-5, 2010, Fogelman Executive Conference Center, University of Memphis. Tennessee
URL:  http://www.membis.org/

RSNA 2010
November 28 - December 3, 2010, McCormick Place, Chicago, IL
URL:  http://www.rsna.org/

4th Workshop on Small Animal SPECT
Center for Gamma-Ray Imaging, University of Arizona, December 8-10, 2010, Tucson, AZ.
URL: http://www.radiology.arizona.edu/CGRI/workshop

2010 International Chemical Conference of Pacific Basin Societies (Pacifichem)
Biomarkers: PET/SPECT Imaging(#105)
December 15-20, 2010, Honolulu, HI
URL: http://www.pacifichem.org/symposia/c_symp_105.htm

RSNA Clinical Trials Methodology Workshop
January 15-21, 2011, Scottsdale, AZ
URL:  http://www.rsna.org/Research/educational_courses.cfm

Multimodality Molecular Imaging of Prostate Cancer
Friday, January 21, 2011, Palm Springs, California
Part of the SNM 2011 Mid-Winter Meetings
URL:  http://www.snm.org/prostate2011

ISMRM Workshop on Ultra High Field Systems & Applications: 7T & Beyond:  Progress, Pitfalls & Potential, Lake Louise, Alberta, Canada - 21-23 February 2011
URL:  http://www.ismrm.org/workshops/UltraHighField10/

Breast Cancer Imaging: State of the Art 2011: Diagnosis, Therapy and Beyond
April 21-22, 2011, Bethesda, Maryland
The Natcher Center, National Institutes of Health
URL:  http://www.snm.org/breast2011

2011 NIH Regional Seminars on Program Funding and Grants Administration: Phoenix, AZ & Ft. Lauderdale, FL (NOT-OD-10-129)
April 27-29, 2011 - Phoenix, AZ: (Registration expected to open early November 2010).
June 22-24, 2011 - Ft. Lauderdale, FL: (Registration expected to open early 2011).
URL:  http://grants.nih.gov/grants/guide/notice-files/NOT-OD-10-129.html

19th ISMRM Scientific Annual Meeting & Exhibition
Montreal, Quebec, Canada - 7-13 May 2011
URL:  http://www.ismrm.org/meetings-workshops/future-ismrm-meetings/

The Cancer Imaging Program at NCI has created this e-mail distribution list to notify interested people about funding opportunities and other issues related to imaging research. Its primary purpose is to call your attention to important, relevant information on NIH Web pages, or in the NIH Guide. Occasionally it may be used to clarify areas of confusion, or disseminate answers to frequently asked questions.
If you wish to remain on the list, no action is necessary. If you wish to be added to the list, please contact Dr Barbara Croft by return e-mail   (bc129b@nih.gov).
Please include your complete mailing address, title, phone and fax numbers.
Cancer Imaging Program, Division of Cancer Treatment and Diagnosis, NCI
6130 Executive Boulevard - MSC-7412
Bethesda, MD 20892-7412
Tel: 301 496 9531Fax: 301 480 3507